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 Post subject: DNA Tells Students They Aren't Who They Thought
PostPosted: Thu 14 Apr 2005 14:33 
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http://www.nytimes.com/2005/04/13/nyregion/13penn.html?

DNA Tells Students They Aren't Who They Thought
By EMMA DALY
Published: April 13, 2005

STATE COLLEGE, Pa. - When Don R. Harrison Jr. was growing up in
Philadelphia, neighborhood children would tease him and call
him "white boy," because his skin was lighter than theirs. But Mr.
Harrison, a "proud black man," was still unprepared for the results
of a DNA test, taken as part of a class at Pennsylvania State
University, to determine his genetic ancestry.

"I figured it would be interesting. I'm light-skinned and I wanted to
know my whole makeup," said Mr. Harrison, a 20-year-old sociology
major. But he was shocked by results showing him to be 52 percent
African and 48 percent European: "which I had no clue about,
considering both my parents are black," said Mr. Harrison. "So I'm
half white."

Samuel M. Richards, who teaches Sociology 119, Race and Ethnic
Relations, to 500 students each semester, said the DNA tests, which
were conducted last year for the first time, were very popular with
the class.

"Everyone wants to take the test, even students who think they are
100 percent one race or another, and almost every one of them wants
to discover something, that they're 1 percent Asian or something.
It's a badge in this multicultural world," he said.

About half of the 100 students tested this semester were white, he
said, "And every one of them said, 'Oh man, I hope I'm part black,'
because it would upset their parents.

"That's this generation," he said. "People want to identify with this
pop multiracial culture. They don't want to live next to it, but they
want to be part of it. It's cool."

The tests also help to deepen conversations about race, he said.

"When I teach I try to demonstrate to students how complex race and
ethnicity are," Dr. Richards said. "My secondary goal is to improve
race relations, and when people discover that what they thought about
themselves is not true - 'I thought I was black, but I'm also Asian
and white' - it leads them to have a different kind of conversation
about race. It leads them to be less bigoted, to ask the deeper
questions, to be more open to differences."

Mark D. Shriver, associate professor of anthropology and genetics at
Penn State, took cheek swabs from about 100 student volunteers in Dr.
Richards's class for the DNA tests.

Many students were surprised by the results of the test, which was
created by Professor Shriver and his commercial partners at DNAPrint
Genomics Inc. to measure genetic mixing in populations, because of
the potential importance of racial or ethnic background to drug
trials, and also because of the researchers' curiosity about their
own ancestry. The company analyzed the test results free; the results
will go into a database for Dr. Shriver's research.

The test compares DNA with that of four parent populations, western
European, west African, east Asian and indigenous American, and the
company claims it is more than 90 percent accurate.

Many unexpected results can be explained by family history. Mr.
Harrison, for instance, recalled a great-grandfather who "would cross
for white, he was so fair."

"The white women apparently found him attractive, and black women
would flock to him because light was in back then." Mr. Harrison
added, "He worked on the railroad, and he looked white in a black-and-
white photo."

Natasha Best, a 21-year-old public relations major, has always
thought of herself as half black and half white, because her mother
is Irish-Lithuanian and her father West Indian. But the test proved
her to be 58 percent European and 42 percent African.

"I was surprised at how much European I was, because though my
father's family knows there is a great-great-grandfather who was
Scottish, no one remembered him," said Ms. Best, who grew up in
Yonkers. "I knew it was true, because I have dark relatives with blue
eyes, but to bring it up a whole 8 percent, that was shocking to me."

But Professor Shriver explained that although a great-great-
grandparent would contribute on average 6.25 percent of a person's
genes, any one ancestor might be represented at a higher or lower
level in today's generation.

Modern migration patterns are also leaving a mark. Ms. Best and Mr.
Harrison are members of the fastest-growing ethnic grouping in the
United States, one that was acknowledged in the 2000 census for the
first time: mixed race. Yet the two students identify themselves in
very different ways.

"I am 48 percent white - genetically I am, at least, but not
culturally. And the fact that I'm black is more important, because
it's something I know. It's who I'm comfortable with," Mr. Harrison
said.

"Some people think it's funny that I consider myself Irish and
celebrate St. Patrick's Day," Ms. Best said, "because no matter how
you cut it, when you look at me you don't think, there goes a white
girl."

She has noted discrimination on both sides. "Black people have told
me I shouldn't date white people," said Ms. Best, whose boyfriend is
white. Some of her white friends say their parents, too, disapprove
of interracial dating. "Other people have told me I'm not really
black, or I think I'm better than other black people because I'm
lighter."

Mr. Harrison, who says that as a child he molded himself to be more
black, does not want this new information to change his
identity. "Just because I found out I'm white, I'm not going to act
white," he said. "I'm very proud of my black side."

But whatever his genes say, or those of Ms. Best, they will most
likely be seen as black - at least by white Americans - for the rest
of their lives.

"I think the test is really interesting; I had to know," said Ms.
Best. "But it makes me question, why are we doing this? Why do
people, especially in this country, want to know? Why are we, as a
people, so caught up in race? Maybe we haven't progressed as much as
we thought we had."

DNAPrintTM genomics, Inc http://www.dnaprint.com/

African Ancestry http://www.africanancestry.com/

AncestryByDNA http://www.ancestrybydna.com/


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 Post subject: Geographic Society Is Seeking a Genealogy of Humankind
PostPosted: Thu 14 Apr 2005 22:46 
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Quote:
April 13, 2005
Geographic Society Is Seeking a Genealogy of Humankind
By NICHOLAS WADE

A five-year project to reconstruct a genealogy of the world's populations and the migration paths of early humans from their ancestral homeland in Africa will be started today by the National Geographic Society and I.B.M., the society said in a statement.

The goal of the program is to collect 100,000 blood samples from indigenous populations around the world and analyze them genetically. Researchers at 10 local centers and at the National Geographic Society in Washington will then assign the people who give blood to lineages that trace the routes traveled by their early ancestors.

The program is an effort to accomplish the goals of the Human Genome Diversity Project, an initiative that was proposed by population geneticists in 1991.

That project ran into a political furor that prevented it from receiving substantial government support. It was denounced by some cultural anthropologists, who said that looking for genetic differences among populations was tantamount to racism. And advocates for indigenous peoples portrayed it as a "vampire project" for extracting valuable medical information from the blood of endangered tribes while giving nothing in return.

The proponents viewed their plan as complementing the Human Genome Project, then getting under way, because it would show how the sequence of DNA units in the human genome varied from one population to another. The project did proceed on a more modest basis, eventually collecting blood samples from 52 populations that were converted into 1,000 cell lines. The first major analysis, published in 2002, showed that the subjects' genomes fell into five major clusters corresponding to their continent of origin and, in effect, to their race.

This and many other studies have established that the branches of the human family tree on different continents coalesce to a single root, the ancestral human population that began to migrate from northeast Africa some 50,000 years ago. The routes of this migration are known in general outline but many details remain to be filled in.

The National Geographic's program, if it succeeds, will create a collection of blood samples 100 times larger than the Human Genome Diversity Project did. Dr. Spencer Wells, a population geneticist at the society who is leading the program, said he hoped to head off charges of exploitation by offering money to the tribes for education and cultural preservation.

Many indigenous peoples believe their ancestors have always lived in their home territory, a credo that will not be supported by genetic analysis of their blood samples. Dr. Wells said that he would "tell people up front" that some of the results may contradict what they believe. "The idea that we have all come on a journey from a common origin is intriguing to people," he said.

The program will cost at least $40 million over five years, a National Geographic Society spokeswoman said. Sources of support include the Waitt Family Foundation of San Diego and the income expected from members of the public, who will be encouraged to send in cheek swabs and learn for $99.95 which male or female lineage they belong to.

Male lineages, based on the Y chromosome, and female lineages, based on mitochondrial DNA, are mostly confined to specific continents, reflecting the fact that until recently people mostly lived and procreated in the place they were born.

Dr. Luca Cavalli-Sforza, the Stanford University population geneticist who was a leading proponent of the Human Genome Diversity Project, said the National Geographic effort would "be a major addition to our knowledge." Dr. Cavalli-Sforza, a pioneer of population genetics, is an adviser to the program.

But Dr. Kenneth Kidd, a population geneticist at Yale University, expressed reservations about the plan to preserve the blood samples as raw DNA. Because the DNA is finite, it cannot be shared with every scientist who may ask for some. In the Human Genome Diversity Project, by contrast, white blood cells from a sample were made essentially immortal before storage. Though it would cost an additional $200 to $300 to immortalize each sample, the cells last forever and the supply is inexhaustible.

The National Geographic program will develop a lot of useful information "but to me it is not a properly and fully developed kind of study" because the samples cannot be made available to everyone in the scientific community, Dr. Kidd said.

Dr. Wells said a large amount of DNA would be available from the 5 to 10 milliliters of blood drawn in each sample. He cited the extra cost of making permanent cell lines and also said that some indigenous peoples opposed the notion of having their cells live on after their deaths.

Besides tracing the routes of early human migrations, the National Geographic program will study other questions of population history like the origin of the Han Chinese, the lost homeland of the Indo-European languages and whether a genetic trail was left by the armies of Alexander the Great.



http://www.nytimes.com/2005/04/13/national/13gene.html


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 Post subject: Re: Geographic Society Is Seeking a Genealogy of Humankind
PostPosted: Fri 15 Apr 2005 13:23 
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Joined: Fri 26 Nov 2004 21:14
Posts: 5517
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Powell wrote:
Quote:
April 13, 2005
Geographic Society Is Seeking a Genealogy of Humankind
By NICHOLAS WADE

A five-year project to reconstruct a genealogy of the world's populations and the migration paths of early humans from their ancestral homeland in Africa will be started today by the National Geographic Society and I.B.M., the society said in a statement.

I sincerely hope that this project gets off the ground, but it faces an serious uphill struggle. The opposition that destroyed the similar project fourteen years ago is even stronger and more powerful today. What's more, this opposition is operating from a basis of knowledge and successful experience of how to stop such projects. The scientists, on the other hand, have never succeeded in the PR game. As I understand it, Native American and Australian Aboriginal tribal councils have already denounced the new project and forbidden their members from donating DNA samples.

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